Free Web NovelChapter 1532: Chapter 725: Nobel-Level Achievements
Through the validation of "Law of Cause and Effect," Zhao Yi had determined his analysis that the detection mechanism during the immune response was indeed using protein sorting as the "detection password."
He announced the results of his inference publicly but did not assert it as an absolute fact.
In many experimental studies, imagination and judgment are very important; it’s not always necessary to validate a judgment since many cannot be verified.
That was the case now.
Without being certain of further results, it was impossible to conduct experimental validations.
Therefore, Zhao Yi directly arranged the following tasks: conducting protein exclusion studies.
Regarding the proteins that might be associated with immune rejection, there were more than eleven types, and not every type within a protein was necessarily directly related.
This was a definite conclusion.
They had to screen out the related ones and eliminate those that were unrelated.
Protein exclusion research was quite complex. It was possible to understand the eleven associated proteins in this way: they were all proteins distributed on the surface of human cell membranes.
Some proteins would participate in the detection of immune response, while others had different functions.
To detect which of these proteins were directly related to the immune response, they had to individually extract each one for experimental testing and then inject the isolated proteins into a target body.
The target and the protein extraction target had to be from the same source.
The best option would have been the human body, rather than some organs, parts, or blood, but since they had not yet applied for voluntary experimental participation, they could only use other methods to assist research.
Then the process became even more complicated.
For each protein, many experiments had to be conducted, and after obtaining data, a detailed analysis was needed with numerous comparisons to determine the relevance to immune response.
Analyzing relevance was very difficult because there was no definitive method, so they could only constantly analyze the available data.
The laboratory still had confidence in this work.
Because Zhao Yi was there.
Zhao Yi was the top mathematician, extremely sensitive to numbers and always able to identify the critical elements.
Therefore, everyone in the laboratory had a lot of confidence; the entire laboratory devoted their energy to the research of protein exclusion, including several researchers, more than a dozen associate researchers, and even more than a dozen assistant researchers.
The laboratory was a hive of activity, with experiments and reports everywhere.
Zhao Yi sat in the central office, continually reviewing the experimental designs and results brought to him. This busy state continued for about a week before they finally obtained affirmative results.
The laboratory convened a summary meeting.
Zhao Yi announced, "Through a series of experiments and analysis, we have determined that seven proteins are directly related to immune detection, while the other four proteins are not."
He passed a report to everyone, detailing the comparative results of the data in the experiments.
Without this clear report, facing a huge amount of experiments and data would cause a headache for anyone, but with the data comparisons in the report, they could clearly see that the results were divided into two types of data situations: the data for seven types of proteins were similar, which was one situation, while the data for the other four types of proteins were another. frёewebηovel.cѳm
This clearly indicated that the seven listed proteins were directly related to immune detection.
"Based on the conclusions of the previous experiment, we can infer that the key to immune detection lies in the arrangement of these seven proteins."
Zhao Yi went to the whiteboard and drew a diagram showing the human cell membrane with an antenna-like protrusion consisting of a series of seven circles. He explained, "This is the key to immune detection."
"People with different blood types have different blood group antigens on their red blood cells, and by blood group antigens, we are still referring to proteins on the surface of the cell membrane."
"We all know that different blood group antigens mean different protein expressions. For example, the molecular bonds at the ends of the antigen proteins in A and B blood types are slightly different."
"However, for people with the same blood type, the antigen proteins are consistent, and when the antigen proteins are consistent, the immune detection can bypass the first phase, and that is the first step."
"Even among people with the same blood type, there can be certain immune rejection responses—why is that? It’s because immune detection has a second step, which is also the most critical: protein sequence detection."
"The seven proteins we discovered are all directly related to immune detection, with different people having different combinations of protein arrangements."
"The checkpoints on the cells have corresponding arrangement detections, and detecting different protein arrangements will trigger an immune response."
After finishing his explanation, Zhao Yi paused to give everyone time to digest the information; then he continued, "Seven proteins could result in five thousand and forty possible arrangements."
"In other words, the same blood type can exhibit five thousand and forty different immune characteristics."
"These are the conclusions we drew from analyzing experimental data; it is only a possibility, but we can design validation experiments based on this."
"For instance, identifying people who have the same immune characteristics."
"Whoosh—"
After Zhao Yi finished his last sentence, it instantly sparked a lively discussion in the meeting room.
